Matrix-immobilized yeast for large-scale production of recombinant human lactoferrin†

486 | Med. Chem. Commun., 2015, 6, 486–491 This journal is © The R Department of Biochemistry, Yong Loo Lin School of Medicine, and Synthetic Biology Research Program, Life Sciences Institute, National University of Singapore, 28 Medical Drive, Singapore 117456. E-mail: [email protected] † Electronic supplementary information (ESI) available. See DOI: 10.1039/ c4md00537f ‡ Author contribution: H. C. L. and M. W. C. conceived and designed the project. H. C. L. performed the experiments. K. L. contributed in gene cloning. H. C. L., I. Y. H. and M. W. C. conducted data analysis and interpretation and wrote the manuscript. M. W. C. supervised the project. Fig. 1 A. Crystal structure of hLF (PDB ID indicated from the blue to red colour cerevisiae expression of recombinant hL homology of hLF against simian and porc eny tree of lactoferrins from various sourc Cite this: Med. Chem. Commun., 2015, 6, 486